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We are currently working on
three major projects (below) and a variety of smaller projects.
Development of a reverse genetic tool for
Phytophthora.
The project is based on the TILLING (targeting induced local
lesions in genomes) strategy developed with
Arabidopsis. Our objectives are to adapt
this approach to Phytophthora and to develop an educational
program highlighting the importance of small genetic
lesions (single nucleotide polymorphisms, SNP's) in living
organisms.

Population resource and genome sequence of the vegetable
pathogen Phytophthora capsici.
Includes (i) sequencing an inbred isolate of P. capsici to 2X
coverage via shotgun sequencing through the
Joint Genome Institute Community Sequencing Program (JGI-CSP),
(ii) 20-30X coverage of the same
isolate and (iii) 2X coverage of four additional outbred isolates
using a novel high throughput sequencing
approach from the company 454 Life Sciences.
 
Characterization of genes expressed by Phytophthora sojae
during the earliest time points in infection. This
project includes gene discovery using fabricated arrays,
confirmation of candidate genes using real time PCR, and
finally, disruption using the Tilling tool.
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